SPRAVATO® (esketamine) Treatment for Depression

Now Available at Our Skokie and Downers Grove Locations

Skyway Behavioral Health is proud to be a certified SPRAVATO® treatment center, offering this innovative treatment option for individuals struggling with treatment-resistant depression (TRD) or major depressive disorder (MDD) with suicidal thoughts or actions.

SPRAVATO® (esketamine) is an FDA-approved nasal spray used in conjunction with an oral antidepressant and is available exclusively at REMS-certified treatment centers like ours.

SPRAVATO® Treatment for Depression

What Is SPRAVATO®?

SPRAVATO® is a prescription medication administered as a nasal spray under direct medical supervision. It’s designed for adults who have not responded to traditional antidepressant treatments or who are experiencing suicidal thoughts in the context of major depression.

Unlike oral antidepressants that can take weeks to work, SPRAVATO® can begin to show effects more rapidly for some individuals.

Please note: SPRAVATO® is not intended for use as an anesthetic or for at-home use. It must be administered at a certified treatment center under observation.

Why Choose Skyway for SPRAVATO®?

At Skyway Behavioral Health, we understand how frustrating and painful it can be to live with depression that doesn’t improve despite trying multiple treatments.

Our experienced care team in Skokie and Downers Grove are here to support you through every step of your SPRAVATO® treatment journey.

We provide:

What to Expect

Before Treatment
If you and your provider determine that SPRAVATO® is right for you, we’ll guide you through a simple intake process. We’ll review your medical history, confirm insurance coverage, and answer any questions you may have.

During Treatment
SPRAVATO® is self-administered under medical supervision in one of our comfortable treatment rooms. Each session requires at least two hours of observation as our staff monitors for side effects such as sedation, dissociation, or changes in blood pressure or breathing. You’ll need someone to drive you home after each session.

After Treatment
You should not drive or operate machinery until the next day, following a full night of restful sleep. Our team will schedule your next session and provide guidance on what to expect as you continue treatment.

Is SPRAVATO® Right for You?

SPRAVATO® may be an option if you:

  • Have tried at least two other antidepressants without improvement

  • Are experiencing major depressive disorder with suicidal thoughts or behaviors

  • Have been referred by a provider for advanced depression treatment options

Please speak with your healthcare provider about whether SPRAVATO® is appropriate for your specific condition.

Ben's Story

Nicole's Story

Safety and Side Effects

SPRAVATO® can cause side effects such as sedation, dizziness, nausea, dissociation, and increased blood pressure. Because of these effects, the treatment must be administered in a clinical setting under observation.

Learn more by reviewing the SPRAVATO® Medication Guide.

Start Your Journey

We’re here to help you reclaim your life. Contact us to find out if SPRAVATO® treatment is right for you or to schedule an assessment.